Machine Learning-Based Prediction of Sepsis Onset in ICU Patients: A Multicenter Prospective Study

Kevin L. Zhao, PhD; Patricia M. O'Brien, MD, PhD; Steven J. Anderson, MD; Rachel K. Patel, MS

Background: Early detection of sepsis remains a critical challenge in intensive care. This study develops and validates a machine learning model for predicting sepsis onset up to 6 hours before clinical recognition. Methods: We collected data from 1...