Open Access | Peer-Reviewed | International Journal ISSN: 3070-6017 (Online)

Current Issue

Volume 2, Issue 1 (2025)

Published: March 31, 2025

Current Issue
review

Advances in Minimally Invasive Cardiac Surgery: A Comprehensive Review of Current Techniques and Outcomes

Background: Minimally invasive cardiac surgery (MICS) has evolved significantly over the past two decades, offering patients reduced surgical trauma and faster recovery. This comprehensive review examines the current state of MICS techniques, their c...

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Efficacy of Combined Immunotherapy and Targeted Therapy in Advanced Non-Small Cell Lung Cancer: A Randomized Controlled Trial

Background: The combination of immunotherapy with targeted therapy for advanced non-small cell lung cancer (NSCLC) remains an active area of investigation. This randomized controlled trial evaluates the efficacy and safety of pembrolizumab combined w...

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case report

Rare Presentation of Bilateral Adrenal Hemorrhage Following COVID-19 Vaccination: A Case Report and Literature Review

We present a rare case of bilateral adrenal hemorrhage in a 54-year-old male presenting with acute abdominal pain, hypotension, and fatigue three days following COVID-19 mRNA vaccination. Computed tomography revealed bilateral adrenal gland enlargeme...

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Machine Learning-Based Prediction of Sepsis Onset in ICU Patients: A Multicenter Prospective Study

Background: Early detection of sepsis remains a critical challenge in intensive care. This study develops and validates a machine learning model for predicting sepsis onset up to 6 hours before clinical recognition. Methods: We collected data from 1...

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Novel Three-Dimensional Printed Patient-Specific Surgical Guides for Complex Pelvic Fracture Fixation

Background: Complex pelvic fractures present significant surgical challenges due to irregular anatomy and limited visualization. This study evaluates the feasibility and accuracy of three-dimensional (3D) printed patient-specific surgical guides for ...

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